Tires are one of the core components of your vehicle and are the driving force, literally! The slightest damage in the tires can be deleterious. Damaged tires not only affect the drive but can also lead to a grave loss if not detected in time. The right and well-maintained set of tires ensure safety, provide better support when driving, and enhance fuel economy.
It is imperative to be vigilant about the condition and ensure that they are in the best condition. The entire vehicle is supported by the tires and thus they play an important role in ensuring the overall performance and well-being. Here are some of the steps to ensure that tires go a long way, in prime condition.
Regular tire pressure checks – An important task is that tire pressure checks must be regularly undertaken as they directly impact the car’s efficiency. When the tires are underinflated, they are at an increased risk of getting damaged or even popping when running over a sharp object. Moreover, the right pressure levels ensure that you enjoy a comfortable ride minus all the bumps. It is extremely simple to check on the tire pressure using an air hose and a tire gauge. Remember that tires must not be over-inflated too as this can be equally damaging.
Rotate once a year – Tires must be rotated to keep the tire wears even. This task involves swapping the front tires with the rear one at least once a year. The rear tires experience greater abuse, and this means that they wear out much faster than the front ones. Alternately, car tires can be rotated after every 7,000 miles or be very vigilant.
Go easy – Speeding down the roads is not only dangerous for the passengers but also does major harm to the tires. Like with most things you own, abusing tires will shorten the amount of time they will last. The constant stomping of breaks can cause the tires to wear off faster. Moreover, one must try and avoid objects that can cause possible harm to the tire. Even the smallest rock could hurt the tires if they are over or underinflated.
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Bathroom showerheads – The ultimate sanitary essentials
Read moreNothing can step up your mood as much as the accessories in the bathroom. A bathroom is where one can have a relaxing shower to rejuvenate the body after a long, tiring day. Similarly, there is no better way to start the day than with a nice, good quality bathroom showerhead releasing water to freshen you up. While fixed bathroom showerheads relieve you from the hassles of handling the equipment, handheld ones allow you to fulfill different bath requirements. Bathroom showerheads that are movable but also capable of being mounted on a base are highly preferred by customers.
A bathroom showerhead is an equipment that contains a nozzle for dispensing water in the form of a shower. For those of you who do not believe in a bucket bath and swear by the pleasure of taking a shower, bathroom shower heads are more than just dcor accessories. Apart from providing a sleek look, they are essential to enhance the functionality of the bathroom. Sometimes, a hose is attached to a shower head for extra convenience during bathing. Bathroom showerheads come in different shapes and designs to satisfy varying sanitary requirements.
- Fixed bathroom showerheads These are the most common form of bathroom showerheads typically found in traditional bathrooms. They are connected to a water pipeline inside the wall just like a regular water tap but at a significant height. Some of them may also be affixed to a ceiling wherein the water falls directly on the head of the individual with the help of gravity. Fixed bathroom showerheads are easy to attach to the already existing plumbing arrangements and do not require much alteration in the hardware.
- Handheld bathroom showerheads While handsets use a hose for additional maneuverability, they can also be made to sit on a fixed platform just like a fixed bathroom showerhead. These can be converted to any form on any given day to fulfill different needs and uses.
- Shower panel A panel comprises of numerous showerheads that are strategically placed to spray water on different parts of the body. You will find a shower panel in large, modern bathrooms that boast of state-of-the-art accessories. While most of the bathroom showerheads are fixed on the wall, one or two of them might allow some movement.
- Adjustable bathroom showerheads These are equipped with control options that provide adjustments in the pressure of water. Adjustable showerheads that come with various settings and options can be modified as per individual bathing demands.
Before buying a bathroom showerhead, it is advisable to measure the dimensions of the bathroom. All big brands send their personnel to help prospective customers in this regard who then suggest the right equipment for a safe shower experience.
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How immunotherapy treatment helps in multiple myeloma
Read moreMultiple myeloma is a life-threatening form of blood cancer that starts in the plasma cells of the blood. Myeloma cells accumulate in the bone marrow and slowly degenerate the kidneys and bones of the body. Also called plasma cell myeloma, it is not completely curable. Multiple myeloma is very challenging to treat and is the second most common cancer in the US.
Diagnosis occurs when abnormal plasma cells are detected in the bone marrow, and treatment is worked out around controlling organ damage. Immunotherapy is a blanket term that describes various cancer treatment methods. Cancer treatment includes the following:
- Chemotherapy
- Stem cell transplantation
- Radiation
- Medications
Immunotherapy helps in cancer treatment for multiple myeloma patients by focusing on three approaches:
- Reversing tumor mediated immune paralysis: This is done using immunomodulatory drugs and by blocking inhibitory molecules or activating stimulatory molecules.
- By stimulating myeloma specific immune responses: This is done using vaccines that work by stimulating an immune response against tumor specific antigen or substances that the body considers foreign.
- Selectively eliminating the malignant clones: This is done by removing T-cells from the body, thereby genetically engineering and reintroducing them into the body. T-cells start multiplying and then locate and destroy the tumor cells.
The U.S. Food and Drug Department recently approved two drugs for relapsed multiple myeloma treatment. One of the drugs is approved for patients who have already been treated with three therapies. It is a first in class immunotherapy treatment (a monoconal antibody) which works when the patient has become resistant to other treatments or when the disease spreads in a very short span of time. The other drug prods the immune system to attack cancer cells. It is for patients who have undergone one to three therapies earlier.
Cancer treatment has potential side effects:
- Infusion related reaction
- Tiredness and difficulty in breathing
- Back pain
- Fever and nausea
- Persistent cough
- Low count of red blood cells, white blood cells, and platelets
Immunotherapy and precision medicine as cancer treatment options work for multiple myeloma patients. A better understanding of causes behind relapse and undertaking new therapies to overcome that resistance is the key to immunotherapy cancer treatment.